Novel Anti-Microbial Peptides of Xenorhabdus Origin Against Multidrug Resistant Plant Pathogens
نویسندگان
چکیده
András Fodor1, Ildikó Varga1, Mária Hevesi2, Andrea Máthé-Fodor3, Jozsef Racsko4,5 and Joseph A. Hogan5 1Plant Protection Institute, Georgikon Faculty, University of Pannonia, Keszthely, 2Department of Pomology, Faculty of Horticultural Science, Corvinus University of Budapest Villányi út Budapest, 3Molecular and Cellular Imaging Center, Ohio State University (OARDC/OSU), OH, 4Department of Horticulture and Crop Science, Ohio State University (OARDC/OSU), OH, 5Valent Biosciences Corporation, 870 Technology Way, Libertyville, IL, 6Department of Animal Sciences, Ohio State University (OARDC/OSU) OH, 1,2Hungary 3,4,5,6USA
منابع مشابه
Anti-virulence potential of eugenol-rich fraction of Syzygium aromaticum against multidrug resistant uropathogens isolated from catheterized patients
Objective: Considering the emergence of biofilm-associated pathogens with multidrug resistance, the objective(s) of the present study was to evaluate the anti-virulence property of Syzygium aromaticum extracts/fractions against 2 multidrug-resistant catheter isolates. Materials and Methods: Pulverized clove buds were subjected to bioactivity-guided isolation to identify the bioactive extract/fr...
متن کاملExpression and antimicrobial activity analysis of dermaseptin B1 recombinant peptides in tobacco transgenic plants
Recently, new molecular breeding and genetic engineering approaches have emerged to overcome the limitations of conventional breeding methods in generating disease-resistance transgenic plants. The use of antimicrobial peptides (AMPs) to produce transgenic plants resistant to a wide range of plant pathogens has achieved great success. Among huge number of AMPs, Dermaseptin B1 (DrsB1), an antimi...
متن کاملThe effect of antibacterial synergism of silver nanoparticles with extract of Urtica dioica and Allium hirtifolum against multidrug resistant klebsiella (MDR) isolated from ICU patients
Background: Because most bacteria responsible for hospital infections are resistant to common antibiotics, the tendency to produce effective and nontoxic anti-microbial drugs have increased. Therefore, it is attempted to substitute antibiotics with natural products, such as nanoparticles and plant extracts. The aim of this study was to investigate the synergistic antibacterial effects of silver...
متن کاملAntibacterial Activities of Amphiphilic Cyclic Cell-Penetrating Peptides against Multidrug-Resistant Pathogens
Multidrug-resistant pathogens have become a major public health concern. There is a great need for the development of novel antibiotics with alternative mechanisms of action for the treatment of life-threatening bacterial infections. Antimicrobial peptides, a major class of antibacterial agents, share amphiphilicity and cationic structural properties with cell-penetrating peptides (CPPs). Herei...
متن کاملCloning and Expression of Two New Recombinant Antimicrobial Dermaseptin B1 Peptides in Tobacco to Control the Growth of Human Bacterial Pathogens
Background and purpose: Rapid emergence of traditional antibiotic-resistant pathogens is one of the most important global challenges in medical sciences. To this end, substitution of current antibiotics with strong antimicrobial peptides could be of great benefit. Materials and methods: In this study, the DNA sequence encoding dermaseptin B1 (DrsB1) antimicrobial peptide derived from Phyllomed...
متن کامل